MenA-IN-2 (Compound 11) is an inhibitor of 1,4-dihydroxy-2-naphthoate prenyltransferase ( MenA ). MenA-IN-2 inhibits MenA with an IC 50 value of 22 µM and inhibits Mycobacterium tuberculosis ( Mtb ) with an GIC 50 value of 10 µM. MenA-IN-2 can curb the continuous transmission of Mtb .
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