7-Chlorokynurenic acid

Overview

7-Chlorokynurenic acid (7-CKA) is a potent and selective antagonist of the glycine B coagonist site of the N-methyl-D-aspartate (NMDA) receptor ( IC 50 =0.56 μM). 7-Chlorokynurenic acid is also a potent inhibitor of the reuptake of glutamate into synaptic vesicles with a K i of 0.59 μM. 7-Chlorokynurenic acid has potent antinociceptive actions after neuraxial delivery.

Application

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Product Information

• Catalog No.: HY-100811
• CAS No.: 18000-24-3
• Molecular Formula: C10H6ClNO3
• Molecular Weight: 223.61
• Purity: 99.86%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 1.43 mg/mL (6.40 mM); Clear solution
• Availability: In-stock

Source

Original product source