Saclofen

Overview

Saclofen is an orally active and a competitive GABA B receptor antagonist with an IC 50 of 7.8 μM. Saclofen has weak antagonistic effects on GABA B1b and GABA B2 heterodimeric recombinant receptors. Saclofen inhibits the binding of Baclofen ( HY-B0007 ) to rat cerebellar membranes and blocks Baclofen -induced circadian phase shifts, and exhibits anti-inflammatory and analgesic effects in rats.

Application

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Product Information

• Catalog No.: HY-100813
• CAS No.: 125464-42-8
• Molecular Formula: C9H12ClNO3S
• Molecular Weight: 249.72
• Purity: 99.97%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source