ISR-IN-1

Overview

ISR-IN-1 is an integrated stress response (ISR) inhibitor targeting eIF2B . ISR-IN-1 enhances eIF2B guanine nucleotide exchange factor activity, stabilizes eIF2B heteropentamer dimers via symmetrical protein-protein interface binding, and releases global protein synthesis inhibition from phosphorylated eIF2α α . ISR-IN-1 can be used for the research of prion disease.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > CNS Infection | Products > Disease Areas > Prion Disease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Infection | Products > Signaling Pathways > Eukaryotic Initiation Factor (eIF)

Product Information

• Catalog No.: HY-153074
• CAS No.: 1628478-15-8
• Molecular Formula: C22H22Cl2F2N2O4
• Molecular Weight: 487.32
• Purity: 98.92%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Availability: In-stock

Source

Original product source