PF-6870961

Overview

PF-6870961 is an inverse agonist of GHSR1a with K i values of 73.6 nM (human GHSR ), 239 nM (rat GHSR ), and 217 nM (dog GHSR ), respectively. PF-6870961 inhibits the constitutive GHSR1a-induced IP accumulation with an IC 50 value of 300 nM. PF-6870961 also inhibits constitutive GHSR1a β-arrestin mobilization with an IC 50 value of 1.10 nM.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > GHSR

Product Information

• Catalog No.: HY-153095
• CAS No.: 2857112-06-0
• Molecular Formula: C29H32N6O2S
• Molecular Weight: 528.67
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source