6PPD-Q

Overview

6PPD-Q (6PPD-Quinone) is an environmental pollutant that can be detected in human urine and is widely present in the environment. 6PPD-Q targets and binds to CNR2 , CNR1 , AA2AR , LCAT , and TRPA1 , with CNR2 exhibiting the highest binding affinity, potentially acting as a CNR2 receptor agonist to activate cannabinoid receptors. 6PPD-Q induces intestinal inflammation and barrier damage by disrupting mitochondrial function, reducing neuronal glycolysis metabolites and TCA cycle intermediates, and exacerbating α-synuclein (α-syn) aggregation. 6PPD-Q is applicable in research on environmental toxicology, neurodegenerative diseases, and inflammation-related disorders.

Application

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Product Information

• Catalog No.: HY-153169
• CAS No.: 2754428-18-5
• Molecular Formula: C18H22N2O2
• Molecular Weight: 298.38
• Purity: 99.77%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: 1.25 mg/mL (4.19 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source