AN15368

Overview

AN15368 is an orally active trypanocidal agent and a prodrug of AN14667. AN15368 selectively targets CPSF3 -mediated mRNA maturation in intracellular amastigotes of Trypanosoma cruzi , reducing the mRNA levels of the parasite . As a prodrug, AN15368 can be cleaved into its active carboxylate form by CBP of Trypanosoma cruzi . AN15368 completely clears long-term naturally acquired Trypanosoma cruzi infections in non-human primates. AN15368 can be used in the research of Chagas disease.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Parasitic Infection | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Others | Products > Research Areas > Infection | Products > Signaling Pathways > Parasite | Products > Signaling Pathways > mRNA

Product Information

• Catalog No.: HY-153238
• CAS No.: 2152662-92-3
• Molecular Formula: C20H28BNO6
• Molecular Weight: 389.25
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source