JY-2

Overview

JY-2 is a moderately selective and orally active Forkhead transcription factor forkhead box O1 ( FoxO1 ) inhibitor that inhibits FoxO1 transcriptional activity with an IC 50 of 22 μM. JY-2 shows moderate inhibition against FoxO3a and FoxO4. JY-2 shows anti-diabetic activity.

Application

Products | Products > Disease Areas > Glucose Metabolism | Products > Disease Areas > Lung Fibrosis | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Respiratory Disease | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Pulmonary Disease | Products > Disease Areas > Digestive System Inflammation | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > FOXO

Product Information

• Catalog No.: HY-153347
• CAS No.: 339103-05-8
• Molecular Formula: C13H7Cl2N3O
• Molecular Weight: 292.12
• Purity: 99.75%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source