Timapiprant sodium

Overview

Timapiprant sodium (OC000459 sodium) is a potent, selective, and orally active D prostanoid receptor 2 ( DP 2 , also known as CRTH2 ) antagonist. Timapiprant sodium (OC000459 sodium) potently displaces [ 3 H] PGD2 from human recombinant DP 2 ( K i =13 nM), rat recombinant DP 2 ( K i =3 nM), and human native DP 2 ( K i =4 nM). Timapiprant sodium (OC000459 sodium) inhibits mast cell activation of Th2 lymphocytes and eosinophils.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Endocrinology | Products > Signaling Pathways > Prostaglandin Receptor

Product Information

• Catalog No.: HY-15342A
• CAS No.: 950688-14-9
• Molecular Formula: C21H16FN2NaO2
• Molecular Weight: 370.35
• Purity: 98.71%
• Storage: 4°C, stored under nitrogen, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
• Solubility: ≥ 2.08 mg/mL (5.62 mM); Clear solution
• Availability: In-stock

Source

Original product source