Emivirine (MKC-442) is a non-nucleoside reverse transcriptase inhibitors (NNRTIs) with K i values of 0.20 and 0.01 μM for dTTP- and dGTP-dependent DNA or RNA polymerase activity, respectively. Emivirine displays potent and selective anti-human immunodeficiency virus type 1 ( HIV-1 ) activity.
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