PROTAC BTK Degrader-3

Overview

PROTAC BTK Degrader-3 is an orally active PROTAC degrader targeting BTK , with a DC 50 value of 10.9 nM. PROTAC BTK Degrader-3 has an IC 50 of 6.3 nM against wild-type BTK and an IC 50 of 8 nM against BTK C481S . PROTAC BTK Degrader-3 can be used in cancer-related research. (Pink: Btk ligand ( HY-150885 ); Blue: Cereblon ligand ( HY-14658 ); Black: linker ( HY-W125996 )).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > Btk

Product Information

• Catalog No.: HY-153536
• CAS No.: 2563861-90-3
• Molecular Formula: C41H40N10O5
• Molecular Weight: 752.82
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source