MS934

Overview

MS934 is a novel improved VHL-recruiting MEK 1/2 PROTAC degrader. MS934 also degrades CRAF . MS934 can be used for the research of variety of human cancers, such as melanoma, nonsmall cell lung cancer (NSCLC), colorectal cancer , primary brain tumors, and hepatocellular carcinoma. (Pink: MEK1 and MEK2 ligand ( HY-168288 ); Blue: VHL ligand ( HY-112078 ); Black: linker ( HY-168289 )).

Application

Products | Products > Disease Areas > Lung Cancer | Products > Disease Areas > Respiratory Cancer | Products > Disease Areas > Colorectal Cancer | Products > Disease Areas > Digestive System Cancer | Products > Disease Areas > Liver Cancer | Products > Disease Areas > Non-Small Cell Lung Cancer | Products > Disease Areas > Cancer | Products > Disease Areas > Respiratory Disease | Products > Disease Areas > Digestive System Disease | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > MEK | Products > Signaling Pathways > Raf

Product Information

• Catalog No.: HY-153863
• CAS No.: 2756323-15-4
• Molecular Formula: C52H69F3IN7O6S
• Molecular Weight: 1104.11
• Purity: 98.48%
• Storage: -20°C, protect from light, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
• Solubility: ≥ 1.25 mg/mL (1.13 mM); Clear solution
• Availability: In-stock

Source

Original product source