Lucitanib (E-3810) is a novel dual inhibitor of VEGFR and FGFR , potently and selectively inhibits VEGFR1 , VEGFR2 , VEGFR3 , FGFR1 and FGFR2 with IC 50 s of 7 nM, 25 nM, 10 nM, 17.5 nM, and 82.5 nM, respectively.
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