VU 0357121

Overview

VU 0357121 is a positive and highly selective mGlu5R allosteric modulator (PAM) with an EC 50 of 33 nM. VU 0357121 is inactive or very weakly antagonizing at other mGlu receptor subtypes.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > mGluR

Product Information

• Catalog No.: HY-15393
• CAS No.: 433967-28-3
• Molecular Formula: C17H17F2NO2
• Molecular Weight: 305.32
• Purity: 99.73%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: 2.5 mg/mL (8.19 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source