URAT1&XO inhibitor 2

Overview

URAT1&XO inhibitor 2 (Compound BDEO) is a dual inhibitor of xanthine oxidase and URAT1 , with IC 50 of 3.3 μM for xanthine oxidase . URAT1&XO inhibitor 2 blocks uptake of uric acid in HEK293 cells expressing URAT1 , with a K i value of 0.145 μM. URAT1&XO inhibitor 2 decreases serum urate level and uric acid excretion in hyperuricemic mice. URAT1&XO inhibitor 2 can be used for research of hyperuricemia.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Metabolic Disease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > URAT1 | Products > Signaling Pathways > Xanthine Oxidase

Product Information

• Catalog No.: HY-153972
• CAS No.: 1239488-96-0
• Molecular Formula: C14H12BrNO3
• Molecular Weight: 322.15
• Purity: 98.69%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 5 mg/mL (15.52 mM); Clear solution
• Availability: In-stock

Source

Original product source