mPGES1-IN-3 (Compound 17d) is a potent and selective microsomal prostaglandin E2 synthase-1 ( mPGES-1 ) inhibitor, which exhibits excellent mPGES-1 enzyme ( IC 50 : 8 nM), cell (A549 IC 50 : 16.24 nM) and human whole blood potency (IC 50 : 249.9 nM).
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > PGE synthase
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