RS-127445

Overview

RS-127445 is a selective, high affinity, orally bioavailable 5-HT 2B receptor antagonist with a pK i of 9.5. RS-127445 shows 1000 fold selectivity for this receptor as compared to numerous other receptor and ion channel binding sites.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Alzheimer's Disease | Products > Disease Areas > Parkinson's Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > 5-HT Receptor

Product Information

• Catalog No.: HY-15419A
• CAS No.: 199864-87-4
• Molecular Formula: C17H16FN3
• Molecular Weight: 281.33
• Purity: 99.95%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 1 mg/mL (3.55 mM); Clear solution
• Availability: In-stock

Source

Original product source