Glycerol dioleate

Overview

Glycerol dioleate is a lipid capable of forming Lyotropic Liquid Crystal (LLC) . When formulated with phosphatidylcholine and exposed to aqueous media, glycerol dioleate constructs an inverted hexagonal (H II ) phase structure with sustained-release properties. The in-situ forming gel prepared by optimizing glycerol dioleate with phosphatidylcholine and N-methyl-2-pyrrolidone enables stable release of Risperidone ( HY-11018 ) for up to 60 days in vitro and in vivo . Glycerol dioleate causes minimal side effects in rabbits, making it an ideal carrier component for the development of antischizophrenia agents. Note : Lyotropic liquid crystals (Lyotropic Liquid Crystal, LLC) are ordered fluid phases self-assembled by amphipathic molecules (e.g., lipids, surfactants ) in solvents (usually water) at specific concentrations.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Schizophrenia | Products > Signaling Pathways > Others | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Biochemical Assay Reagents

Product Information

• Catalog No.: HY-154487
• CAS No.: 25637-84-7
• Molecular Formula: C39H72O5
• Molecular Weight: 621.00
• Purity: 98.0%
• Storage: -20°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Availability: In-stock

Source

Original product source