VU 0364439

Overview

VU 0364439 is a mGlu4 positive allosteric modulator with an EC 50 of 19.8 nM. VU 0364439 modulates the GRM4 / CBX4 / HIF-1α signaling pathway by enhancing GRM4 - CBX4 interaction . VU 0364439 can be used for the research of parkinson’s disease.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Parkinson's Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > VEGFR | Products > Signaling Pathways > mGluR | Products > Signaling Pathways > HIF/HIF Prolyl-Hydroxylase | Products > Signaling Pathways > PDK-1

Product Information

• Catalog No.: HY-15476
• CAS No.: 1246086-78-1
• Molecular Formula: C18H13Cl2N3O3S
• Molecular Weight: 422.29
• Purity: 99.42%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (5.92 mM); Clear solution
• Availability: In-stock

Source

Original product source