YS-49

Overview

YS-49 is a PI3K/Akt (a downstream target of RhoA) activator, to reduce RhoA/PTEN activation in the 3-methylcholanthrene-treated cells. YS-49 inhibits angiotensin II (Ang II) -stimulated proliferation of VSMCs via induction of heme oxygenase (HO)-1. YS-49 is also an isoquinoline compound alkaloid, has a strong positive inotropic action through activation of cardiac β-adrenoceptors .

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Endocrinology | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Akt | Products > Signaling Pathways > PI3K | Products > Signaling Pathways > Angiotensin Receptor | Products > Signaling Pathways > Adrenergic Receptor

Product Information

• Catalog No.: HY-15477
• CAS No.: 132836-42-1
• Molecular Formula: C20H20BrNO2
• Molecular Weight: 386.28
• Purity: 99.98%
• Storage: 4°C, stored under nitrogen, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
• Solubility: ≥ 2.5 mg/mL (6.47 mM); Clear solution
• Availability: In-stock

Source

Original product source