PROTAC α-synuclein degrader 5

Overview

PROTAC α-synuclein degrader 5 is a highly selective small-molecule degrader ( PROTAC ) of α-synuclein aggregates, with a DC 50 of 7.51 μM and the highest degradation rate D max of 89%. PROTAC α-synuclein degrader 5 contains probe molecule sery308 and E3 ligase ligands. PROTAC α-synuclein degrader 5 can be used for neurological disease research .

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > α-synuclein

Product Information

• Catalog No.: HY-155021
• CAS No.: 2781922-42-5
• Molecular Formula: C39H41N7O10
• Molecular Weight: 767.78
• Purity: 99.80%
• Storage: -20°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
• Solubility: ≥ 3.75 mg/mL (4.88 mM); Clear solution
• Availability: In-stock

Source

Original product source