PROTAC BTK Degrader-5

Overview

PROTAC BTK degraders-5(compound 3e) is a selective BTK PROTAC degrader with a DC 50 value of 7.0 nM in JeKo-1 cells. PROTAC BTK degraders-5 has no off-target effect on degrading CRBN neosubstates. PROTAC BTK degraders-5 has anti-proliferation effect on various lymphoma tumor cells and can be used in chronic lymphoid malignancies research. (Pink: Btk ligand ( HY-150898 ); Blue: Cereblon ligand ( HY-W440230 ); Black: linker ( HY-168297 )).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > Btk

Product Information

• Catalog No.: HY-155072
• CAS No.: 3049086-75-8
• Molecular Formula: C52H57ClFN9O6
• Molecular Weight: 958.52
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source