PZ-1922 free base

Overview

PZ-1922 free base is a BBB-penetrable 5-HT6R/5-HT3R antagonist (K i : 17 nM, 0.45 nM for 5-HT6R/5-HT3R respectively). PZ-1922 free base reversibly inhibits MAO-B (pIC 50 : 8.93). PZ-1922 free base reverses Scopolamine (SCOP) (HY-N0296) induced memory deficits in the novel object recognition (NOR) test in rats. PZ-1922 free base prevents Aβ-induced memory decline in the T-maze test.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > 5-HT Receptor | Products > Signaling Pathways > Monoamine Oxidase

Product Information

• Catalog No.: HY-155330A
• CAS No.: 1648745-65-6
• Molecular Formula: C22H21ClN4
• Molecular Weight: 376.88
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source