Antileishmanial agent-19

Overview

Antileishmanial agent-19 (Compound F27) is an antileishmanial agent, with a IC 50 of 3.39 μM for L. donovani promastigotes . Antileishmanial agent-19 inhibits Leishmania prolyl-tRNA synthetase . Antileishmanial agent-19 inhibits host PI3K/Akt/CREB axis-mediated IL-10 secretion. Antileishmanial agent-19 induces autophagy-mediated apoptosis in L. donovani promastigotes . Antileishmanial agent-19 reduces parasite burden in L.d-infected animals .

Application

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Product Information

• Catalog No.: HY-155520
• CAS No.: 3049715-81-0
• Molecular Formula: C22H18N4O3
• Molecular Weight: 386.40
• Purity: 99.45%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source