Anti-NASH agent 1

Overview

Anti-NASH agent 1 (compound 3d)，a derivative of Elafibranor ( HY-16737 )，is a potent agonist of PPAR-α/δ ，targeting to nonalcoholic steatohepatitis (NASH). Anti-NASH agent 1 (3-10 mg/kg; 4 weeks) improves hyperlipidemia，liver fat degeneration and liver inflammation in Methionine-choline deficiency (MCD) induced NASH mice model. Anti-NASH agent 1 shows low liver toxicity and potent liver protection effect.

Application

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Product Information

• Catalog No.: HY-155525
• CAS No.: 2409685-41-0
• Molecular Formula: C26H33NO4
• Molecular Weight: 423.54
• Purity: 98.49%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: 2.5 mg/mL (5.90 mM); Clear solution; Need ultrasonic
• Availability: In-stock

Source

Original product source