VcMMAE

Overview

VcMMAE (mc-vc-PAB-MMAE) is a agent-linker conjugate for ADC with potent antitumor activity by using the anti-mitotic agent, monomethyl auristatin E (MMAE, a tubulin inhibitor), linked via the lysosomally cleavable dipeptide, valine-citrulline (vc).

Application

Products | Products > Signaling Pathways > Antibody-Drug Conjugate/ADC Related | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Cytoskeleton | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Drug-Linker Conjugates for ADC | Products > Signaling Pathways > Microtubule/Tubulin

Product Information

• Catalog No.: HY-15575
• CAS No.: 646502-53-6
• Molecular Formula: C68H105N11O15
• Molecular Weight: 1316.63
• Purity: 99.95%
• Storage: -20°C, sealed storage, away from moisture and light * The compound is unstable in solutions, freshly prepared is recommended.
• Solubility: ≥ 2.5 mg/mL (1.90 mM); Clear solution
• Availability: In-stock

Source

Original product source