McMMAF

Overview

McMMAF (Maleimidocaproyl monomethylauristatin F) is an active molecule linker for ADC , made by coupling the powerful microtubule inhibitor Monomethyl auristatin F (MMAF) ( HY-15579 ) with the protecting group maleimidocaproyl. McMMAF can be conjugated with anti-BCMA antibodies to form J6M0-mcMMAF, promoting apoptosis and inhibiting tumor growth.

Application

Products | Products > Signaling Pathways > Antibody-Drug Conjugate/ADC Related | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Drug-Linker Conjugates for ADC | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-15578
• CAS No.: 863971-19-1
• Molecular Formula: C49H76N6O11
• Molecular Weight: 925.16
• Purity: 99.97%
• Storage: -20°C, stored under nitrogen * The compound is unstable in solutions, freshly prepared is recommended.
• Solubility: ≥ 5 mg/mL (5.40 mM); Clear solution
• Availability: In-stock

Source

Original product source