Mal-PEG5000-OH can be used as a macroinitiator to obtain amphiphilic diblock copolymers by ring-opening polymerization of LA. Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems. Nanoparticles encapsulate Triptolide ( HY-32735 ), which can avoid the disadvantage of Triptolide ’s poor water solubility and reduce its toxicity.
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