SH491

Overview

SH491 (Compound 33) is an antiosteoporosis agent. SH491 inhibits RANKL-induced osteoclast differentiation on bone-marrow-derived monocytes (BMMs) ( IC 50 : 11.8 nM). SH491 inhibits the expression of osteoclastogenesis-related marker genes (TRAP, CTSK, MMP-9 , and ATPase v0d2) and proteins (TRAP, CTSK, MMP-9 ).

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Cathepsin | Products > Signaling Pathways > MMP

Product Information

• Catalog No.: HY-155960
• CAS No.: 2975285-28-8
• Molecular Formula: C33H50N2O
• Molecular Weight: 490.76
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source