RDN2150

Overview

RDN2150 is a ZAP-70 inhibitor with an IC 50 of 14.6 nM, and it exhibits selectivity for Syk over other kinases. RDN2150 inhibits signal transduction and activation of T cells/CAR-T cells, reduces the phosphorylation level of Erk1/2 , suppresses the induction of CD69 and IL-2 , and downregulates phosphotyrosine signaling pathways including hnRNP sites in T cells. RDN2150 can be used for psoriasis-related research.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Tyrosinase | Products > Signaling Pathways > Interleukin Related | Products > Signaling Pathways > ERK | Products > Signaling Pathways > IFNAR

Product Information

• Catalog No.: HY-155978
• CAS No.: 2839429-51-3
• Molecular Formula: C28H29ClN8O4
• Molecular Weight: 577.03
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source