WLB-89462

Overview

WLB-89462 (Compound 20c) is a selective σ2 receptor ligand ( K i : 13 nM). WLB-89462 has neuroprotective activity. WLB-89462 improves short-term memory impairment induced by Aβ peptide in rats. WLB-89462 has good ADMET profile (good solubility, no CYP inhibition, good metabolic stability, high permeability, brain penetration, and high oral exposure in rodents).

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Sigma Receptor

Product Information

• Catalog No.: HY-155992
• CAS No.: 2849471-75-4
• Molecular Formula: C21H29N5O3
• Molecular Weight: 399.49
• Purity: 98.70%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 5 mg/mL (12.52 mM); Clear solution
• Availability: In-stock

Source

Original product source