L-NIO is a potent, non-selective and NADPH-dependent nitric oxide synthase (NOS) inhibitor, with K i s of 1.7, 3.9, 3.9 μM for neuronal ( nNOS ), endothelial ( eNOS ), and inducible ( iNOS ), respectively. L-NIO induces a consistentfocal ischemic infarctin rats.
Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > NO Synthase
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