MEDS433

Overview

MEDS433 is a potent inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an IC 50 of 1.2 nM. MEDS433 exerts a potent antiviral activity against RSV-A and RSV-B in the one-digit nanomolar range. MEDS433 induces the expression of antiviral proteins encoded by interferon stimulated genes (ISGs) able to reduce RSV replication.

Application

Products | Products > Disease Areas > Infection | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Infection | Products > Signaling Pathways > Lactate Dehydrogenase

Product Information

• Catalog No.: HY-156442
• CAS No.: 2241027-61-0
• Molecular Formula: C20H11F4N3O2
• Molecular Weight: 401.31
• Purity: 99.51%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (6.23 mM); Clear solution
• Availability: In-stock

Source

Original product source