NC1

Overview

NC1 is a selective non-competitive and allosteric lymphoid-specific tyrosine phosphatase ( LYP ) inhibitor, with a K i value 4.3 μM. NC1 allosterically regulates LYP/PTPN22 activity by restricting WPD loop movement. NC1 inhibits LYP activity in lymphoid T cells and enhances T-cell receptor signaling. NC1 can be used for the research of autoimmune diseases.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Phosphatase | Products > Signaling Pathways > ERK

Product Information

• Catalog No.: HY-156659
• CAS No.: 445406-82-6
• Molecular Formula: C29H26N2O7S
• Molecular Weight: 546.59
• Purity: 98.73%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 5 mg/mL (9.15 mM); Clear solution
• Availability: In-stock

Source

Original product source