TLD-1433

Overview

TLD-1433 is the fourth-generation ruthenium (II) based photodynamic compound ( PDC ). TLD-1433 is activated by green light (525 ± 25 nm) and efficiently generates ROS to achieve pathogen inactivation. After photoinactivation, TLD-1433 significantly induces lipid peroxidation of the cell membrane, which can directly damage the integrity of the viral envelope. TLD-1433 has ID 50 for enveloped viruses (such as H1N1 influenza virus , coronavirus OC43 , HSV-1 , Zika virus) is as low as nanomolar level; for non-enveloped viruses (such as adenovirus Ad5, mammalian rotavirus MRV), a concentration of micro-molar level is required for inactivation. TLD-1433 has antigen retention property and can be used for the preparation of inactivated vaccines.

Application

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Product Information

• Catalog No.: HY-156786
• CAS No.: 1471479-22-7
• Molecular Formula: C49H38Cl2N8RuS3
• Molecular Weight: 1007.05
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source