NODAGA-NHS

NODAGA-NHS
  • CAS No.:1407166-70-4
  • Grade:99.98%
  • Formula:C19H28N4O10
  • M.W.:472.45

Overview

NODAGA-NHS (NODA-GA-NHS ester) is the activated ester form of the NODAGA chelator. NODAGA-NHS conjugates with Trastuzumab ( HY-P9907 ) to form NODAGA-Trastuzumab, a conjugate that can chelate 64 Cu for the preparation of radiotracers. NODAGA-NHS covalently binds to the amino group of lactosamine derivatives to form radiotracer precursors. [ 64 Cu]NODAGA-trastuzumab enables PET imaging of tumors expressing HER2 . NODAGA-NHS is used in studies of HER2 -positive breast cancer and ovarian adenocarcinoma.

Application

Products | Products > Disease Areas > Ovarian Cancer | Products > Disease Areas > Urogenital Cancer | Products > Disease Areas > HER-2 Positive Breast Cancer | Products > Disease Areas > Cancer | Products > Disease Areas > Urogenital Disease | Products > Disease Areas > Breast Cancer | Products > Signaling Pathways > JAK/STAT Signaling | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > Antibody-Drug Conjugate/ADC Related | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > EGFR | Products > Signaling Pathways > Radionuclide-Drug Conjugates (RDCs)

Product Information

  • Catalog No.: HY-156991
  • CAS No.: 1407166-70-4
  • Molecular Formula: C19H28N4O10
  • Molecular Weight: 472.45
  • Purity: 99.98%
  • Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
  • Availability: In-stock

Source

Original product source


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