Istaroxime oxalate (PST2744 oxalate) is the oxalate form of Istaroxime ( HY-15718 ). Istaroxime oxalate is is an inotropic agent, that inhibits Na + /K + -ATPase with an IC 50 of 0.11 μM. Istaroxime oxalate increases force of contraction in guinea pig atria and twitch amplitude in isolated guinea pig myocytes without causing lethal arrhythmias.
Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Na+/K+ ATPase
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