TM38837 is an orally active and selective inverse agonist of cannabinoid receptor 1 ( CB1 ) with an IC 50 of 24 nM. TM38837 has higher selectivity for CB1 than for CB2 (IC 50 : 4500 nM). TM38837 can reduce body weight, improve plasma inflammatory markers and glucose homeostasis.
Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Cannabinoid Receptor
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