PDEδ autophagic degrader 1

Overview

PDEδ autophagic degrader 1 (compound 12c), an autophagosome-tethering compound (ATTEC) . is a potent PDEδ autophagic degrader. PDEδ autophagic degrader 1 reduces the PDEδ protein level through lysosome-mediated autophagy without affecting the PDEδ mRNA expression. PDEδ autophagic degrader 1 suppresses the growth in KRAS mutant pancreatic cancer cells.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Signaling Pathways > ATTECs | Products > Signaling Pathways > Phosphodiesterase (PDE) | Products > Signaling Pathways > Autophagy

Product Information

• Catalog No.: HY-157458
• CAS No.: 3054112-59-0
• Molecular Formula: C41H42Br2IN7O5
• Molecular Weight: 999.53
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source