hAChE-IN-7

Overview

hAChE-IN-7 (compound 5s) is a mixed inhibitor affecting both the catalytic active site (CAS) and peripheral anionic site (PAS) of hAChE. hAChE-IN-7 displays the balanced inhibitory effect on hAChE ( IC 50 =69.8 nM) and hBuChE ( IC 50 =68.0 nM), and exhibits inhibitory activity against β-secretase-1 (BACE-1) (IC 50 =3.6 μM). hAChE-IN-7 has the potential for Alzheimer's disease (AD) research.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Cholinesterase (ChE) | Products > Signaling Pathways > Beta-secretase

Product Information

• Catalog No.: HY-157527
• CAS No.: 2978613-03-3
• Molecular Formula: C38H55N3O3
• Molecular Weight: 601.86
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source