XPC-5462 is a selective Na V 1.6/1.2 inhibitor, with an IC 50 of 0.0103 μM against hNa V 1.6 , 0.0137 μM against mNa V 1.6 , and 0.0109 μM against hNa V 1.2 . XPC-5462 significantly reduces epileptiform discharges. XPC-5462 is applicable for epilepsy-related research.
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