Brexpiprazole-d 8

Overview

Brexpiprazole -d 8 (OPC-34712-d 8 ) is the deuterium labeled Brexpiprazole ( HY-15780 ). Brexpiprazole (OPC-34712), an atypical orally active antipsychotic agent, is a partial agonist of human 5-HT1A and dopamine D 2L receptor with K i s of 0.12 nM and 0.3 nM, respectively. Brexpiprazole is also a 5-HT2A receptor antagonist with a K i of 0.47 nM. Brexpiprazole also shows potent antagonist activity at human noradrenergic α1B ( K i =0.17 nM) and α2C receptors ( K i =0.59 nM) .

Application

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Product Information

• Catalog No.: HY-15780S
• CAS No.: 1427049-21-5
• Molecular Formula: C25H19D8N3O2S
• Molecular Weight: 441.62
• Purity: 99.0%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source