Antimalarial agent 38

Overview

Antimalarial agent 38 is an orally active antimalarial agent, which inhibits Plasmodium falciparum D6 strain, Chloroquine ( HY-17589A )-sensitive Thai strain and Chloroquine -resistant FcB1 strain and K1 strain, with IC 50 s of 0.5, 13, 1 and 13 μM, respectively. Antimalarial agent 38 is non-cytotoxic for mammalian cells MCR58 (IC 50 >140 μM). Antimalarial agent 38 improves the survival rate of Plasmodium yoelii nigeriensis infected mouse model.

Application

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Product Information

• Catalog No.: HY-157892
• CAS No.: 123580-46-1
• Molecular Formula: C36H40N2O12
• Molecular Weight: 692.71
• Purity: 99.98%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 2.5 mg/mL (3.61 mM); Clear solution
• Availability: In-stock

Source

Original product source