FR173657

Overview

FR173657 is an orally active bradykinin B2 receptor antagonist ( IC 50 : 0.56, 1.5, 2.9 nM for pig, rat, human B2 receptor respectively). FR173657 (p.o.) inhibits BK-induced bronchoconstriction in guinea-pigs (ED 50 : 0.075 mg/kg). FR173657 (p.o.) also inhibits Carrageenin-induced paw oedema in mice (ED 50 : 6.8 mg/kg). FR173657 can be used for research of inflammatory disease.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Bradykinin Receptor

Product Information

• Catalog No.: HY-15791
• CAS No.: 167838-64-4
• Molecular Formula: C30H27Cl2N5O4
• Molecular Weight: 592.47
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source