GPR183 antagonist-3

Overview

GPR183 antagonist-3 (compound 33) is an oral active GPR183 antagonist with the IC 50 of 8.7 μM. GPR183 antagonist-3 displays strong in vitro antimigration and anti-inflammatory activity in monocytes, and improves the pathological symptoms of DSS-induced experimental colitis.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Viral Infection | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > EBI2/GPR183

Product Information

• Catalog No.: HY-157939
• CAS No.: 3054870-33-3
• Molecular Formula: C21H19BrN4O2S
• Molecular Weight: 471.37
• Purity: 98.79%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 5 mg/mL (10.61 mM); Clear solution
• Availability: In-stock

Source

Original product source