DOTA-GA-maleimide

Overview

DOTA-GA-maleimide is a bifunctional chelator with protein conjugation and radiometal chelation capabilities. DOTA-GA-maleimide forms stable complexes with 111 In and conjugates with proteins via maleimide chemistry. DOTA-GA-maleimide conjugates with LFn , enabling 111 In radiolabeling of LFn through direct or pre-labeling strategies. Radiolabeled LFn is applicable to MMP activity imaging studies. DOTA-GA-maleimide is used in cancer research.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Others | Products > Signaling Pathways > Antibody-Drug Conjugate/ADC Related | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Signaling Pathways > Biochemical Assay Reagents | Products > Signaling Pathways > Radionuclide-Drug Conjugates (RDCs) | Products > Signaling Pathways > MMP

Product Information

• Catalog No.: HY-157977
• CAS No.: 1800229-46-2
• Molecular Formula: C25H38N6O11
• Molecular Weight: 598.60
• Purity: 99.72%
• Storage: -20°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Availability: In-stock

Source

Original product source