mG2N001

Overview

mG2N001 is a negative allosteric modulator (NAM) ( IC 50 : 93 nM) of the metabotropic glutamate receptor mGluR2 and binds to mGluR2 as an antagonist (Ki: 63 nM). mG2N001 is microparticle- and plasma-stable, and its radioisotope [11C] mG2N001 can be used in PET imaging. [11C] mG2N001 has good brain heterogeneity and brain penetration, and can selectively accumulate in mGluR2-rich regions, producing high-contrast brain images.

Application

Products | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Others | Products > Signaling Pathways > mGluR | Products > Signaling Pathways > Src

Product Information

• Catalog No.: HY-157998
• CAS No.: 2760515-88-4
• Molecular Formula: C18H19FN2O3
• Molecular Weight: 330.35
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source