HDAC6-IN-37

Overview

HDAC6-IN-37 (compound W5) is an inhibitor of HDAC6 and has neuroprotective effects. HDAC6-IN-37 can restore the morphology of hippocampal neurons, reduce the expression of Aβ, Tau, and p-Tau proteins in the hippocampus of AD rats, and inhibit the formation of senile plaques and neurofibrillary tangles. Thus, HDAC6-IN-37 improves the Aβ/Cu 2+ -induced AD model in rats, regulates oxidative stress status, and balances neurotransmitter disorders in brain tissue.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > HDAC

Product Information

• Catalog No.: HY-158030
• CAS No.: 2986486-82-0
• Molecular Formula: C19H16ClN3O2S
• Molecular Weight: 385.87
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source