PROTAC STING Degrader-2

Overview

PROTAC STING Degrader-2 is a STING PROTAC degrader with a DC 50 of 0.53 μM. PROTAC STING Degrader-2 reduces the phosphorylation levels of TBK1 and IRF3 . PROTAC STING Degrader-2 decreases the mRNA expression levels of IFN-β , CXCL10 and TNF-α , and blocks luciferase secretion. PROTAC STING Degrader-2 can be used in the research of autoimmune diseases.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Autoimmune Disease | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > CXCR | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > STING | Products > Signaling Pathways > IKK | Products > Signaling Pathways > IFNAR

Product Information

• Catalog No.: HY-158036
• CAS No.: 3023095-61-3
• Molecular Formula: C74H79FN10O15S3
• Molecular Weight: 1463.67
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source