PROTAC PARP1 degrader-1

Overview

PROTAC PARP1 degrader-1 is a PARP1 PROTAC degrader with a DC 50 value of 252.5 nM. PROTAC PARP1 degrader-1, combined with Daunorubicin ( HY-13062A ), induces the accumulation of cytoplasmic DNA fragments, activates the cGAS / STING innate immune pathway, and remodels the tumor microenvironment. PROTAC PARP1 degrader-1 can be used in research related to breast cancer . (Pink: PARP-1 ligand ( HY-W973851 ); Blue: Cereblon ligand ( HY-41547 ); Black: linker).

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Breast Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Signaling Pathways > PROTACs | Products > Signaling Pathways > PARP

Product Information

• Catalog No.: HY-158045
• CAS No.: 3032324-56-1
• Molecular Formula: C32H28N6O5
• Molecular Weight: 576.60
• Purity: 99.86%
• Storage: 4°C, protect from light, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
• Availability: In-stock

Source

Original product source